Day 1 - Nov. 23, 2015
12:00 Adelaide Fernandes (University of Lisbon) 'Welcome to Lisbon, an ageless city'
12:20 Buffet lunch
13:00 Ralph Müller (ETH Zurich) 'Introduction of MouseAGE and Working Group 4'
13:15 Natal van Riel (Eindhoven University of Technology) 'The aims of the workshop'
Session 1: Muskuloskeletal – Bone
Chair: Enrico Dall'Ara
13:20 Enrico Dall'Ara (University of Sheffield) '4D measurements of bone changes in the mouse tibia'
13:40 Bert van Rietbergen (Eindhoven University of Technology) 'Analysis of bone strength and structural adaptation in vivo'
14:00 Sara Checa (Charité - Universitätsmedizin Berlin) 'Age-related changes in the mechanical regulation of bone adaptation'
14:30 Hanna Isaksson (Lund University) 'Understanding function-structure-composition relationship in bone'
14:50 Ralph Müller (ETH Zurich) 'In silico mechanobiology of bone remodeling'
15:10 Laoise McNamara / Ted Vaughan (National University of Ireland, Galway) 'Future directions in image-derived multiscale computational modelling of bone and marrow'
15:40 Refreshments Break
Session 2: Muskuloskeletal
Chair: Natal van Riel
16:10 Harry van Lenthe (University of Leuven) 'Quantification of bone structure and bone mechanics in aging mice'
16:30 Oliver Röhrle (University of Stuttgart) 'Chemo-Electro-Mechanical Modelling of the Neuromuscular System'
16:50 Bob Wiseman (Michigan State University) - invited speaker 'Translational Medicine: Magnetic Resonance, Modeling and Muscle Metabolism'
17:30 Transfer to hotel
20:00 Workshop Dinner
Day 2 - Nov. 24, 2015
Session 3 - Metabolism
Chair: Natal van Riel
9:00 Salvador Armindo (The University of Coimbra) 'Finding organization principles in antioxidant protection, redox signaling and stress responses through kinetic modeling and systems analysis'
9:20 Jeroen Jeneson (University Medical Centre Groningen) 'Using computational modeling to understand experimental observations on muscle energy metabolism'
9:40 Barbara Bakker (University Medical Centre Groningen) 'Bottom-up and top down modelling of energy metabolism in mice: successes and challenges'
10:00 Natal van Riel (Eindhoven University of Technology) 'Progressive changes in lipoprotein metabolism in mice after pharmacological intervention'
10:20 Coffee break
Session 4 - Cardiovascular
Chair: Ralph Müller
10:40 Sander Land (King's College London) 'A framework for multiscale modelling of the mouse heart'
11:00 Alfonso Bueno-Orovio (University of Oxford) 'Bridging the gap from mouse to human: In silico approaches for translational cardiovascular research'
Session 5 - Towards a digital mouse / What is next…
11:20 Enrico Dall'Ara 'Wrap-up and follow-up actions'
12:00 Take away lunch