Resources

Publications

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

Find drugs that delay many diseases of old age

Research Programmes

RESOLVE

FP7 project RESOLVE extensively uses mouse models to study Metabolic Syndrome and associated diseases, and includes mathematical modelling.

Website: http://www.resolve-diabetes.org/about/

TARGEAR

The TARGEAR project is an Industry-Academia Partnerships and Pathways (IAPP) – Marie Curie Action constituted by experienced research groups in complementary fields ranging from the molecular to the clinical aspects of age-related hearing loss. The general objective is to develop a collaborative strategy between public research institutes and private companies, based in transfer of knowledge, to design and implement preclinical studies for presbyacusis.

Website: http://targear.eu

3R Initiatives

These national initiatives aim to further the principles of replacing, reducing and refining (3Rs) the use of animal models in research.

Databases

- Pre-clinical­Trials­.org: a registry and results database of pre-clinical animal studies conducted around the world with the aim to enhance the quality of disease target validation and to facilitate meta-analyses by combining smaller studies

Websitehttps://preclinicaltrialsorg.compbio.sdu.dk/

- MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity

Website: http://www.mitoage.info/

- DrugAge: a curated database of lifespan-extending drugs and compounds

Website: http://genomics.senescence.info/drugs/