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TAmiRNA presents the new osteomiR test kit – a unique molecular diagnostic kit for detection of osteoporosis

TAmiRNA

The Austrian spin-off TAmiRNA develops biomarker solutions, which significantly improve early detection of serious age-related illnesses such as osteoporosis. At this years American Society for Bone and Mineral Research meeting in Atlanta, Georgia (USA). TAmiRNA presents the new osteomiR test kit – a unique molecular diagnostic kit for detection of osteoporosis.

For those at the ASBMR meeting, please, visit TAmiRNA at booth Nr 613 for some Austrian sweets, information on the osteomiR kit and chance to win a 2-day workshop in Vienna, Austria.

Visit the TAmiRNA website for further information. 

Useful Downloads: 

INFRAFRONTIER-I3 / Mouse Metabolic Phenotyping Training Course

Infrafrontier

10th -13th October 2016 

German Mouse Clinic,Helmholz Centre, Munich  

INFRAFRONTIER, the European Research Infrastructure for phenotyping and archiving of model mammalian genomes, offers an excellent training opportunity in mouse metabolic phenotyping. The course will be run by the German Mouse Clinic (GMC) based at the Helmholtz Centre Munich (https://www.mouseclinic.de/index.html), and will cover state of the art phenotyping assays used in the energy metabolism, diabetes, clinical chemistry and pathology screens of the GMC. All assays are routinely applied in systemic phenotyping projects of the GMC, and in part also in the phenotyping pipeline of the International Mouse Phenotyping Consortium (IMPC). The course will be run by highly experienced scientists of the GMC, and involve presentations and extensive discussions of assays, experimental design and data analyses.

Learning objectives

The 4-day course is intending to give participants a comprehensive overview of state of the art technologies and approaches in mouse metabolic phenotyping. A strong focus will be on experimental design and phenotyping data analyses

Prospective attendees

Course level will be at MS, PhD and Postdoc level. No prior experience with metabolic phenotyping required

Programme

Day 1 / October 10th / starting at 12.00

- German Mouse Clinic phenotyping pipelines, INFRAFRONTIER

- Glucose metabolism, glucose tolerance test

- Clamp technologies

Day 2 / October 11th

- Metabolic phenotyping

- Clinical chemistry / liver enzymes

- Pathology and histological analyses

- Tour of German Mouse Clinic

Day 3 / October 12th

- Phenotyping pipeline design

- Data analysis, statistics

- Liver spectroscopy, Maldi mass spectrometry

- Breath gas analysis

- Metabolomics

- Tour of Helmholtz Genome Analysis Centre (GAC)

Day 4 / October 13th / ending at 17.00

- Pigs as animal models for metabolic research

- Indirect calorimetry

- Human respirometry

Information

The training course is limited to a total of 10 participants

Cost: 500€ covering course materials, accommodation, coffee breaks, lunch and course dinner (but excluding travel cost)

Accommodation for course participants has been arranged in the Kurfürst Hotel close to the meeting venue, http://www.kurfuerst-hotel.de/

Registration deadline: September 16th, 2016

 A registration form can be downloaded from the INFRAFRONTIER portal athttps://www.infrafrontier.eu/resources-and-services/training-and-consulting-services/phenotyping-training-courses

 For further enquiries and submission of applications: training@infrafrontier.eu

The INFRAFRONTIER metabolic phenotyping training course is financially supported by the EC FP7 funded INFRAFRONTIER-I3 project, project No: 312325

 

Job position advertisement

Lab Head/Research Investigator (Ph.D. level)

Musculoskeletal Disease Area – Muscle #194706BR

 

Job Description

The Muscle group in Cambridge, US, is seeking for a highly motivated Ph.D. level scientist to join our early stage drug discovery department. As head of an in vitro research lab with 2 to 3 associates you will be responsible for exploring new muscle disease mechanisms and potential treatments including target identification, validation and subsequent drug discovery research. Our focus is on targeting pathway dysregulation nodes in disease, subsequently identifying drug candidates and profiling them in relevant disease models. In the role, you will be developing in vitro and ex vivo functional and phenotypical assay systems using emerging technologies. You will be part of an interdisciplinary, highly collaborative group.

The successful candidate will be responsible for:

- Conducting cell, molecular biology and biochemistry experiments. 

- Development and implementation of disease-relevant cellular systems with phenotypical and functional readouts using healthy and patient primary and iPS cells.

- Training, developing and mentoring associates and closely collaborating on all levels.

- Independent planning, execution, documentation, analysis and interpretation of experiments.

- Presentation of results in both written and oral format and delivery of completed reports within a multidisciplinary team environment.

 

Requirements

  • Ph.D., MD or DVM in  biochemistry, cell biology, genetics, systems biology, or related field
  • Experience in target identification, validation and working with primary cells, or establishing cellular assays, or extensive cellular signaling experience, with an emphasis on disease pathways would be helpful
  • Experience with physiologic assays using human or patient cells, or iPS cells or functional (e.g. calcium, contraction) or phenotypical readouts would be a plus
  • Is well-organized and used to work in an interdisciplinary team environment.
  • Proficiency in standard informatics tools.
  • Three to five years of experience, ideally in industry or drug discovery: musculoskeletal research experience would be additionally desireable

More information: https://sjobs.brassring.com/tgwebhost/jobdetails.aspx?partnerid=13617&siteid=5260&jobid=2436779&_ga=1.190091491.913167989.1470856948

Meeting: Developing interventions for frailty: what do we measure?

14th - 15th November 2016

InterCityHotel, Vienna, Austria

Confirmed Speakers: Thomas von Zglinicki (Newcastle University, UK), Roger Fielding (Tufts University, USA), Roberto Bernabei (Università Cattolica del Sacro Cuore, Italy), Alexander Bürkle (Universität Konstanz, Germany), Sophie Lemire-Brachat (Novartis, Switzerland), Evgeni Levin-Tsivtsivadze (University of Amsterdam, The Netherlands), Patrik Christen (ETH Zurich, Switzerland) and Clemens Löwik (Erasmus MC, The Netherlands).

There will be a number of bursaries available for researchers to attend the meeting- these will cover accommodation, travel and meals in line with COST reimbursement rules. COST rules on reimbursement are detailed in the COST vademecum which can be found here: http://www.cost.eu/participate. Reimbursement will occur after the meeting.

Abstracts are encouraged to be submitted from the network for poster presentation in the themes of the meeting: ageing and age-related diseases, models of frailty, assessment of frailty, biomarkers of frailty, new technologies for biomarker analysis and measures of performance. Please use the registration form to submit an abstract. Abstracts should be no longer than 300 words.

Please use this form HERE to apply for a bursary and to register your interest in attending.

Deadline for abstract submission and bursary applications: 9th September 2016

Applicants will be notified on the outcome of their application week commencing 19th September 2016.

For queries please contact: mouseage@sheffield.ac.uk

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