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3rd Course Mouse and Rat Bone Phenotyping

== LAST CHANCE for applying to the "3rd Course on Mouse and Rat Bone Phenotyping" ==

=== 31st MAY FINAL DEADLINE===

 

Objective of the Course: The aim of this course is capacitating participants to localize and to interpret the most common skeletal alterations found in mice and rats. This will occur in the context of dedicated learning sessions devoted to the study of bone anatomy, histology, immunohistochemistry, ultrastructure and imaging. Each lecture will be followed by a practical session in which participants will work with real bone specimens,radiographs,histological preparations, and images from TEM and micro-CT. In addition, the course will include seminars where specific skeletal abnormalities found in mutant mice will be discussed.

Duration: 4 days. 10-13 July 2017

Number of participants: 15 max

The course will be held at the Center for Animal Biotechnology and Gene Therapy (CBATEG) and the School of Veterinary Medicine at the Universitat Autònoma de Barcelona (www.uab.cat)

Tuition fee: € 950

DEADLINE FOR APPLICATIONS: 31st May 2017
Applications should be sent to: victor.nacher@uab.cat

Detailed information can be found in Useful Downloads.

Useful Downloads: 

Postdoctoral Research Position at CEDOC, Portugal

Postdoctoral Research Position - Lysosome dysfunction in Age-related macular degeneration

A Postdoctoral position is available in the laboratory of Miguel Seabra, at the CEDOC - Chronic Diseases Research Center, Nova Medical School, Lisbon, Portugal.

In this work we aim to test new therapeutic approaches for Age-related macular degeneration (AMD). We hypothesise that AMD has it origin in the retinal pigment epithelium (RPE) due to chronic dysfunction of the lysosome. Cellular models of AMD will be generated using cell cultures of retinal pigment epithelium (RPE) and will be tested compounds that could improve lysosomal function. The results to be obtained in cellular models will guide future tests in animal models.

This grant is for 6 months, but could be extended if funding is renewed.

Please send your application including your CV, contact details, PhD certificate, a letter of motivation, and the names and contact information of two references to applications@nms.unl.pt with the subject “DAI/2017/14 application” from 10th April to 24th April 2017. More details about this application can be found here. 

ERC Advanced Award

MouseAGE member, Dr. Ralph Müller received this year an Advanced Grant of the European Research Council (ERC). His awarded project,  "MechAGE – In vivo single-cell mechanomics of bone adaptation and regeneration in the aging mouse", is directly related to the MouseAGE activities and was very much inspired by all the discussions had so far in the aim of the consortium about investigating and modeling the aging mouse.

Ralph Müller, Professor of Biomechanics, is interested in how mechanical vibrations influence bone development. His main focus is the understanding of how bones adapt and regenerate over the course of a lifetime. In his ERC project, Müller aims to investigate which cell types are involved in these processes and how these cells react to age-related change. Specifically, he wants to use genome sequencing of single cells to understand how molecular ageing processes under mechanical loads affect bone remodelling. In the future, this understanding may facilitate targeted exercise programmes within the context of personalised medicine to foremost prevent osteoporosis-related bone fractures or at least heal them more quickly.

The project will be funded with a total of 2.5 Million € over the next five years. Such award reinforces the relevance and importance of MouseAGE field of research.

IUBMB Focused Meeting on «Molecular aspects of aging and longevity»

Next MouseAGE annual meeting will take place at Athens in the IUBMB Focused Meeting on «Molecular aspects of aging and longevity»16-19 October, Greece.

International Union of Biochemistry and Molecular Biology (IUBMB) entrusted the organization of this focused meeting to Athens, as it was considered to be the ideal setting for gathering together young researchers and leading investigators from many countries. 

Aging is an inevitable biological process. Unravelling the fundamental molecular mechanisms of aging and longevity is a pre-requisite for developing appropriate means of increasing “healthy lifespan”. The Meeting will focus on these axes as it aims to integrate the latest research developments and new technologies from internationally acknowledged experts as well as to attract young scientists in the field and to give them the opportunity to discuss with experts. Emphasis will be given to young group-leaders and it will have an additional session for presentations by young scientists. Finally, it’ll provide several travel fellowships to young scientists, especially from the developing countries.

Some of already confirmed invited speakers:   

More information at: http://www.iubmb2017aging.org/

 

 

Useful Downloads: 

MouseAGE Working Group 3 Meeting

On the past 28th February, the working group 3 (WG3) met at the COST Association headquarters, in Bruxelles, Belgium.

The aim of the meeting was to the disccus current protocols from the different labs involved in the MouseAGE, concerning the Assessment of Cognition in Aging mice models. Keynote speakers Professor Brun Ulfhake, from Karolinska Institutet, Sweden, and Professor Kathy Magnusson, from Oregon State University, USA, joined for the discussion. Standardization of protocols is one of the major goals of the WG3.

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