Dr Klaus Schughart

Working group 2
Management Committee
Helmholtz Centre for Infection Research
  • Germany

Klaus Schughart is currently Head of Department Infection Genetics at the HZI; professor at the University of Veterinary Medicine, Hannover; visiting professor at the University of Tennessee Health Science Center. Previously he was Deputy scientific director of the HZI Braunschweig betweem 2006-2010. From 2002-2007 he was Head of Department „Programme Planning and Scientific Controlling“ (PWC) and Head of Division „Scientific and Technical Services“ (WTD) at the Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany. From 1997-2001 he was Head of Department of Molecular and Cellular Biology, Transgene, Strasbourg. Previous to this he was a Project Leader in the Helmholtz-Zentrum München (HMGU) from 1995-1996. From 1990-1994 he was a Group Leader at the Max Planck Institute of Immunobiology, Freiburg  Klaus was a  Postdoctoral Fellow at the Yale University, Dept. of Biology, New Haven from 1987-1989.

The main interest of Klaus' research is to identify genetic factors that control the susceptibility or resistance of the host to influenza A virus infections. For this, he is using mouse as a model systems and analyzing various aspects of the host response (e.g. survival, body weight loss, lung pathology, immune response at the cellular and transcriptome level) in mouse genetic reference populations and in mouse knock-out mutants. These studies provided important insights into the genetic background and susceptibility of the host which triggered studies in humans and also identified therapeutic targets for interventions. These activates are building on his long-term experience in mouse genetics and virology education.