Models of Ageing and Disease

Click on a Model title to view any additional information or comments. For queries on any individual model, please contact Ilaria Bellantuono at for further information.
Author(s) Institution(s) Disease/ageing Model Clinically relevant? Useful Downloads
Giovambattista Pani Università Cattolica School of Medicine Mitochondrial dysfunction / dilated cardiomyopathy / early lethality MnSOD (SOD2) deficient mice (C57BL6/J); p66shc KO mice (129/Sv) Yes PDF icon SOD2 x p66 Pani.pdf
Gisela Kuhn/Ariane Scheuren Institute for Biomechanics, ETH Zurich Accelerated Ageing/Osteoporosis PolgAD257A/D257A Yes PDF icon ETHZ.pdf
Coral Sanfeliu, Mercè Pallàs IIBB-CSIC, IDIBAPS, CIBERESP / UB, CIBERNED Accelerated senescence / Alzheimer (traits) SAMP8 Yes PDF icon MouseAGE Database_SAMP8_add-Merce-Pallas.pdf
Coral Sanfeliu, Mercè Pallàs IIBB-CSIC, IDIBAPS, CIBERESP / UB, CIBERNED Alzheimer’s Disease Tg6799 (5XFAD) Yes PDF icon MouseAGE Database_Tg6799_add-Merce-Pallas.pdf
Silvia Murillo-Cuesta, Isabel Varela-Nieto Centro de Investigación Biomédica en Red (CIBER); Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) Age-related hearing loss or presbycusis. Noise-induced hearing loss. Inbred mouse strain C57BL/6J, which has the Cdh23ahl allele Yes PDF icon MC-VN.pdf
Dr Laura Piqueras Research Institute of Health–INCLIVA Abdominal Aortic Aneurysm APOE KNOCKOUT MICE INFUSED WITH ANGIOTENSIN II FOR 28 DAYS Yes PDF icon PIQUERAS.pdf
Angelica Figueroa Conde-Valvís Instituto de Investigación Biomédica A Coruña (INIBIC) Cancer Xenograft assay with 6 week-old athymic nu/nu mice Further studies need to be performed PDF icon Figueroa .pdf, PDF icon Figure 1 (2).pdf
Marina Lynch Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland Alzheimer’s Disease APP/PS1 mice Minimally PDF icon Lynch.pdf